論文
2021年
SLUG is upregulated and induces epithelial mesenchymal transition in canine oral squamous cell carcinoma.
Noguchi S, Hirano K, Tanimoto N, Shimada T, Akiyoshi H. Vet Comp Oncol. 2021 in press.
Radiotherapy-induced tumor lysis syndrome in a dog with thymoma.
Wada Y, Yamazaki H, Tanaka M, Kaneguchi A, Tanaka T, Akiyoshi H, Noguchi S. J Vet Med Sci. 2021 Aug. 83(8):1290-1294.
The NRG3/ERBB4 signaling cascade as a novel therapeutic target for canine glioma.
Noguchi S, Inoue M, Ichikawa T, Kurozumi K, Matsumoto Y, Nakamoto Y, Akiyoshi H, Kamishina H. Exp Cell Res. 2021 Mar. 400(2):112504.
2020年
A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs.
Igase M, Nemoto Y, Itamoto K, Tani K, Nakaichi M, Sakurai M, Sakai Y, Noguchi S, Kato M, Tsukui T, Mizuno T. Sci Rep. 2020 Oct 10(1):18311.
Assessment of biomarkers influencing treatment success on small intestinal lymphoma in dogs.
Yamazaki H, Sasai H, Tanaka M, Tanaka T, Nishida H, Noguchi S, Kuwamura M, Akiyoshi H. Vet Comp Oncol. 2020 Sep.
Establishing cell lines for canine tonsillar and non-tonsillar oral squamous cell carcinoma and identifying characteristics associated with malignancy.
Noguchi S, Hattori A, Tanimoto N, Nishida R, Hirano K, Wada Y, Matsuyama S, Shimada T, Akiyoshi H. Tissue Cell. 2020 10;67:101408.
The inhibitory effect of canine interferon gamma on the growth of canine tumors.
Hamamura Y, Nakagawa T, Okuda M, Noguchi S, Igase M, Mizuno T. Res Vet Sci. 2020 132:466-473.
Tenovin-6 induces the SIRT-independent cell growth suppression and blocks autophagy flux in canine hemangiosarcoma cell lines.
Igase M, Fujiki N, Shibutani S, Sakai H, Noguchi S, Nemoto Y, Mizuno T. Exp Cell Res. 2020 388(1):111810.
An aortic body carcinoma with sarcomatoid morphology and chondroid metaplasia in a French Bulldog.
Morita C, Tanaka M, Noguchi S, Shimamura S, Wada Y, Izawa T, Yamate J, Kuwamura M. J Vet Med Sci. 2020 82:576-579.
2019年
MicroRNA-205 enhances the radiosensitivity of canine melanoma cells by inhibiting E2F1.
Wada Y, Noguchi S, Nishiyama Y, Matsuyama S, Mori T, Igase M, Mizuno T, Shimamura S, Shimada T. Jpn J Vet Res. 2019 67:151-161.
Anti-tumour activity of oncolytic reovirus against canine histiocytic sarcoma cells.
Igase M, Shousu K, Fujiki N, Sakurai M, Bonkobara M, Hwang CC, Coffey M, Noguchi S, Nemoto Y, Mizuno T. Vet Comp Oncol. 2019 17:184-193.
Reovirus changes the expression of anti-apoptotic and proapoptotic proteins with c-kit downregulation in canine mast cell tumor cell lines.
Hwang CC, Igase M, Okuda M, Coffey M, Noguchi S, Mizuno T. Biochem Biophys Res Commun. 2019 517:233-237.
Synthetic microRNA-205 exhibited tumour suppression in spontaneous canine malignant melanoma by intratumoral injection.
Yoshikawa R, Mori T, Noguchi S, Akao Y, Maruo K, Kitade Y. Vet Comp Oncol. 2019 17:407-412.
Establishment of a novel experimental model for muscle-invasive bladder cancer using a dog bladder cancer organoid culture.
Elbadawy M, Usui T, Mori T, Tsunedomi R, Hazama S, Nabeta R, Uchide T, Fukushima R, Yoshida T, Shibutani M, Tanaka T, Masuda S, Okada R, Ichikawa U, Omatsu T, Mizutani T, Katayama Y, Noguchi S, Iwas S, Nakagawa T, Shinohara Y, Kaneda M, Yamawaki H, Sasaki K. Cancer Sci. 2019 110:2806-2821.
PTEN, a target of microRNA-374b, contributes to the radiosensitivity of canine melanoma cells.
Noguchi S, Ogusu R, Wada Y, Matsuyama S, Mori T. Int J Mol Sci. 2019 20:pii: E4631.
Combination Therapy with Reovirus and ATM Inhibitor Enhances Cell Death and Virus Replication in Canine Melanoma.
Igase M, Shibutani S, Kurogouchi Y, Fujiki N, Hwang CC, Coffey M, Noguchi S, Nemoto Y, Mizuno T. Mol Ther Oncolytics. 2019 28:49-59.
2018年
Prognostic significance of midline shift of the olfactory or frontal lobes of the brain in canine nasal carcinomas treated by palliative radiotherapy: a pilot study.
Wada Y, Noguchi S, Sasaki H, Taketomi A, Hamakawa m, Shimamura S, Shimada T. J Vet Med Sci. 2018 80:1724-1727.
Development and characterization of monoclonal antibodies against canine PD-1 and PD-L1.
Nemoto Y, Shosu K, Okuda M, Noguchi S, Mizuno T. Vet Immunol Immunopathol. 2018 198:19-25.
Oncolytic reovirus therapy: Pilot study indogs with spontaneously occurring tumours.
Hwang CC, Igase M, Sakurai M, Haraguchi T, Tani K, Itamoto K, Shimokawa T, Nakaichi M, Nemoto Y, Noguchi S, Coffey M, Okuda M, Mizuno T. Vet Comp Oncol. 2018 16(2):229-238.
Bosutinib, an SRC inhibitor, induces caspase-independent cell death associated with permeabilization of lysosomal membranes in melanoma cells.
Noguchi S, Shibutani S, Fukushima K, Mori T, Igase M, Mizuno T. Vet Comp Oncol. 2018 16(1):69-76.
2017年
Establishment of a dog primary prostate cancer organoid using the urine cancer stem cells.
Usui T, Sakurai M, Nishikawa S, Umata K, Nemoto Y, Haraguchi T, Itamoto K, Mizuno T, Noguchi S, Mori T, Iwai S, Nakagawa T, YamawakiH Ohama T, Sato K. Cancer Sci. 2017 108(12):2383-2392.
2016年
Analysis of microRNA-203 function in CREB/MITF/RAB27a pathway: comparison between canine and human melanoma cells.
Noguchi S, Kumazaki M, Mori T, Baba K, Okuda M, Mizuno T, Akao Y. Vet Comp Oncol. 2016 Dec 14(4):384-394.
The effects of oncolytic reovirus in canine lymphoma cell lines.
Hwang CC, Umeki S, Igase M, Coffey M, Noguchi S, Okuda M, Mizuno T. Vet Comp Oncol. 2016 Aug 1:61-73.
Development of hepatocellular carcinoma after long-term immunosuppressive therapy including danazol in a dog.
Kobayashi K, Shimokawa Miyama T. Itamoto K, Noguchi S, Baba K, Mizuno T, Okuda M. J Vet Med Sci. 2016 78(10):1611-1614.
Programmed Cell Death Ligand 1 expression in canine cancer.
Shosu K, Sakurai M, Inoue K, Nakagawa T, Sakai H, Morimoto M, Okuda M, Noguchi S, Mizuno T. In Vivo. 2016 30(3):195-204.
Expression and localization of epidermal growth factor, transforming growth factor-a and epidermal growth factor receptor in the canine testis.
Tamada H, Takemoto K, Tominaga M, Kawate N, Takahashi M, Hatoya S, Matsuyama S, Inaba T, Sawada T. J Reprod Dev. 2016 62:59-64.
Oncolytic reovirus synergizes with chemotherapeutic agents to promote cell death in canine mammary gland tumor.
Igase M, Hwang CC, Kambayashi S, Kubo M, Coffey M, Miyama TS, Baba K, Okuda M, Noguchi S, Mizuno T. Can J Vet Res. 2016 Jan 80(1):21-31.
2015年
A novel apoptosis-inducing mechanism of 5-aza-2′-deoxycitidine in melanoma cells: Demethylation of TNF-α and activation of FOXO1.
Noguchi S, Mori T, Igase M, Mizuno T. Cancer Lett. 2015 Dec 369(2):344-353.
Acquired Fnaconi syndrome in a dog exposed to jerky treats in Japan.
Igase M, Baba K, Shimokawa-Miyama T, Noguchi S, Mizuno T, Okuda M. J Vet Med Sci. 2015 Dec 77(11):1507-1510.
Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma.
Kambayashi S, Igase M, Kobayashi K, Kimura A, Shimokawa-Miyama T, Baba K, Noguchi S, Mizuno T, Okuda M. J Vet Med Sci. 2015 Dec 77(11):1405-1412.
DNA methylation contributes toward silencing of antioncogenic microRNA-203 in human and canine melanoma cells.
Noguchi S, Mori T, Nakagawa T, Itamoto K, Haraguchi T, Mizuno T. Melanoma Res. 2015 Oct 25(5):390-8.
Expression of O (6)-methylguanine-DNA methyltransferase causes lomustine resistance in canine lymphoma cells.
Kambayashi S, Minami K, Ogawa Y, Hamaji T, Hwang CC, Igase M, Hiraoka H, Miyama TS, Noguchi S, Baba K, Mizuno T, Okuda M. Can J Vet Res. 2015 Jul;79(3):201-9.
Abundance of BER-related proteins depends on cell proliferation status and the presence of DNA polymerase β.
Yamamoto M, Yamamoto R, Takenaka S, Matsuyama S, Kubo K. J Radiat Res. 2015 Jul;56(4):607-14.
The oncolytic effects of reovirus in canine solid tumor cell lines.
Igase M, Hwang CC, Coffey M, Okuda M, Noguchi S, Mizuno T. J Vet Med Sci. 2015 Jun 1;77(5):541-8.
AP endonuclease knockdown enhances methyl methanesulfonate hypersensitivity of DNA polymerase β knockout mouse embryonic fibroblasts.
Yamamoto R, Umetsu M, Yamamoto M, Matsuyama S, Takenaka S, Ide H, Kubo K. J Radiat Res. 2015 May;56(3):462-6.
Cloning and expression analysis of prohibitin mRNA in canine mammary tumors.
Matsuyama S, Nakano Y, Nakamura M, Yamamoto R, Shimada T, Ohashi F, Kubo K. J Vet Med Sci. 2015 Jan;77(1):101-4.
2014年
Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase.
Yamamoto R, Ohshiro Y, Shimotani T, Yamamoto M, Matsuyama S, Ide H, Kubo K. J Radiat Res. 2014 Jul;55(4):707-12.
Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia jurkat cells by modulating expression of fas-associated protein with death domain (FADD).
Yamada N, Noguchi S, Kumazaki M, Shinohara H, Miki K, Naoe T, Akao Y. Biochim Biophys Acta. 2014 Mar 1843(3):590-602.
MicroRNA-203 regulates melanosome transport and tyrosinase expression in melanoma cells by targeting kinesin superfamily protein 5b.
Noguchi S, Kumazaki M, Yasui Y, Mori T, Yamada N, Akao Y. J Invest Dermatol. 2014 Feb 134(2):461-469.
2013年
犬の下垂体腫瘍に対する寡分割3 次元原体照射による 放射線治療の短期的効果.
森 崇、伊藤祐典、山崎美史、村上麻美、野口俊助、山田名美、丸尾幸嗣. 日本獣医師会雑誌. 2013 Oct 66: 709-712.
Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesicles.
Tsugita M, Yamada N, Noguchi S, Yamada K, Moritake H, Shimizu K, Akao Y, Ohno T. PLoS One. 2013 Oct 8(10):e77416. Doi: 10.1371.
Role of intracellular and extracellular microRNA-92a in colorectal cancer.
Yamada N, Nakagawa Y, Tsujimura N, Kumazaki M, Noguchi S, Mori T, Hirata I, Maruo K, Akao Y. Transl Oncol. 2013 Aug 1;6(4):482-492.
3-decenoic acid derivatives induce autophagic cell death through the down-regulation of E2F1.
Shinohara H, Noguchi S, Kumazaki M, Yamada N, Ito T, Oyama M, Ito Y, Otsuki Y, Naito S, Iinuma M, Akao Y. J Toxicol Res. 2013 Jul;3(1):29-34.
Multimodal therapy for the treatment of an oncocytoma in the nasal cavity of a cat.
Mori T, Mishima H, Sakai H, Noguchi S, Maruo K. J Small Anim Pract. 2013 Jul;54(7):390.
鼻腔内腫瘍の犬11症例におけるオルソボルテージを用いた化学放射線療法の予後.
柳瀬沙和子、森 崇、星野有希、伊藤祐典、村上麻美、西谷由莉、野口俊助、酒井洋樹、柳井徳磨、丸尾幸嗣. 獣医麻酔外科学雑誌. 2012 Oct 43(3・4): 41-45.
Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.
Kumazaki M, Noguchi S, Yasui Y, Iwasaki J, Shinohara H, Yamada N, Akao Y. J Nutr Biochem. 2013 Nov 24(11):1849-1858.
Chemically modified synthetic microRNA-205 inhibits the growth of melanoma cells in vitro and in vivo.
Noguchi S, Iwasaki J, Kumazaki M, Mori T, Maruo K, Sakai H, Yamada N, Shimada K, Naoe T, Kitade Y, Akao Y. Mol Ther. 2013 Jun 21;(6):1204-1211.
Tumor-suppressive microRNA-145 targets catenin δ-1 to regulate Wnt/β-catenin signaling in human colon cancer cells.
Yamada N, Noguchi S, Mori T, Naoe T, Maruo K, Akao Y. Cancer Lett. 2013 Jul 28;335(2):332-342.
socs7, a target gene of microRNA-145, regulates interferon-β induction through STAT3 nuclear translocation in bladder cancer cells.
Noguchi S, Yamada N, Kumazaki M, Yasui Y, Iwasaki J, Naito S, Akao Y. Cell Death Dis. 2013 Feb 7;4:e482.
岐阜大学における組織球肉腫好発犬種の動向について
塩川友里菜、森 崇、星野有希、伊藤祐典、野口俊助、酒井洋樹、柳井徳磨、丸尾幸嗣. 日本獣医師会雑誌. 2013 May 66(5):321-324.
Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways.
Noguchi S, Yasui Y, Iwasaki J, Kumazaki M, Yamada N, Naito S, Akao Y. Cancer Lett. 2013 Jan 28:328(2):353-361.
MicroRNAs as tumour suppressors in canine and human melanoma cells and as a prognostic factor in canine melanomas.
Noguchi S, Mori T, Hoshino Y, Yamada N, Maruo K, Akao Y., Vet Comp Oncol. 2013 Jun 11(2):113-123.
2012年
Fascin-1 expression in canine cutaneous and oral melanocytic tumours.
Yamada N, Mori T, Murakami M, Noguchi S, Sakai H, Akao Y, Maruo K. Vet Comp Oncol. 2012 Dec;10(4):303-311.
Anti-oncogenic MicroRNA-203 Induces Senescence by Targeting E2F3 in Human Melanoma Cells.
Noguchi S, Mori T, Otsuka Y, Yamada N, Yasui Y, Iwasaki J, Kumazaki M, Maruo K, Akao Y. J Biol Chem. 2012. Apr 6;287(15):11769-11777.
Comparative Study of Anti-Oncogenic MicroRNA-145 in Canine and Human Malignant Melanoma.
Noguchi S, Mori T, Hoshino Y, Yamada N, Nakagawa T, Sasaki N, Akao Y, Maruo K. J Vet Med Sci. 2012 Feb 1; 74(1):1-8.
NEIL1 mRNA splicing variants are expressed in normal mouse organs.
Yamamoto R, Yamamoto M, Kusaka H, Masatsugu H, Matsuyama S, Tajima T, Ide H, Kubo K. J Radiat Res. 2012;53(2):234-41.
2011年
犬の鼻腔内に発生した血管肉腫の1例
関根一哉，星野有希，森 崇，酒井洋樹，野口俊助，山田名美，山瀬新悟，丸尾幸嗣. 日本獣医師会雑誌. 2011 Nov; 64(11): 893-895.
不完全切除となった犬骨軟骨腫の予後観察
坂井田誠，森 崇，山田雅人，野口俊助，高井有一，酒井洋樹，丸尾幸嗣. 日本獣医師会雑誌. 2011 Nov; 64(11):885-888.
MicroRNA-143 functions as a tumor suppressor in human bladder cancer T24 cells.
Noguchi S, Mori T, Hoshino Y, Maruo K, Yamada N, Kitade Y, Naoe T, Akao Y. Cancer Lett. 2011 Aug 28; 307(2):211-220.
Microvesicle-mediated RNA molecule delivery system using monocytes/macrophages.
Akao Y, Iio A, Itoh T, Noguchi S, Itoh Y, Ohtsuki Y, Naoe T. Mol Ther. 2011 Feb; 19(2):395-399.
Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells.
Akao Y, Noguchi S, Iio A, Kojima K, Takagi T, Naoe T. Cancer Lett. 2011 Jan 28; 300(2):197-204.
放射線療法，選択的シクロオキシゲナーゼ-2阻害剤により長期コントロールが可能であった犬下顎腺癌の2例.
野口俊助，森 崇，星野有希，村上麻美，酒井洋樹，丸尾幸嗣. 日本獣医師会雑誌. 2010 Aug; 63(8): 634-636.
2008年
A novel monofunctional DNA glycosylase activity against thymine glycol in mouse cell nuclei.
Yamamoto R, Akiyama M, Ide H, Yamamoto K, Matsuyama S, Kubo K. J Radiat Res. 2008 May;49(3):249-59.
2007年
Expression patterns of the BRCA1 splicing variants in canine normal tissues and mammary gland tumors.
Sugiura T, Matsuyama S, Akiyosi H, Takenaka S, Yamate J, Kuwamura M, Aoki M, Shimada T, Ohashi F, Kubo K. J Vet Med Sci. 2007 Jun;69(6):587-92.
2005年
Detection of transforming growth factor-alpha and epidermal growth factor receptor mRNA and immunohistochemical localization of the corresponding proteins in the canine uterus during the estrous cycle.
Tamada H, Tominaga M, Kida K, Kawate N, Inaba T, Matsuyama S, Sawada T. Histol Histopathol. 2005 20:817-824.
2003年
Detection of transforming growth factor-alpha and epidermal growth factor receptor mRNA and immunohistochemical localization of their proteins in the ovine uterus during the early implantation period.
Tamada H, Tsubutani D, Kawate N, Inaba T, Matsuyama S, Imakawa K, Sakai S, Christenson R, Sawada T. Histochem J. 2003 34:383-390.
2002年
Enhancement of aromatase gene expression in the mediobasal hypothalamus during anestrus in the beagle bitch.
Inaba T, Namura T, Tani H, Matsuyama S, Torii R, Kawate N, Tamada H, Hatoya S, Kumagai D, Sugiura K, Sawada T. Neurosci Lett. 2002 333:107-110.
2001年
Expression patterns of the erbB subfamily mRNA in canine benign and malignant mammary tumors.
Matsuyama S, Nakamura M, Yonezawa K, Shimada T, Ohashi F, Takamori Y, Kubo K. J Vet Med Sci. 2001 Sep;63(9):949-54.
2000年
Presence of B220 within thymocytes and its expression on the cell surface during apoptosis.
Oka S, Mori N, Matsuyama S, Takamori Y, Kubo K. Immunology. 2000 Aug;100(4):417-23.
ゴールデンリトリバーの腎異形成の一例．
宮本 忠、出村愛実、松山 聡、大橋文人、深田恒夫、馬場栄一郎、桑村 充、山手丈至、小谷猛夫、金 徹準. 動物臨床医学. 2000 Mar 9:137-141.
Substrate specificity of human methylpurine DNA N-glycosylase.
Asaeda A, Ide H, Asagoshi K, Matsuyama S, Tano K, Murakami A, Takamori Y, Kubo K. Biochemistry. 2000 Feb 29;39(8):1959-65.
Successful management of canine acanthomatous epuris with the combination of surgical excision and radiotherapy.
Aoki M, Kubo K, Kuwamura M, Kotani T, Matsuyama S, Shibazaki A, Shimada T, Ohashi F. Jpn J Vet Anesth Surg. 2000 Jan 31:37-41.
1999年
Increased LH pulse frequency and estrogen secretion associated with termination of anestrus followed by enhancement of uterine estrogen receptor gene expression in the beagle bitch.
Tani H, Inaba T, Nonami M, Matsuyama S, Takamori Y, Torii R, Tamada H, Kawate H, Kawate N, Sawada T. Thriogenology. 1999 Jul 52:593-607.
Flow cytometric analysis of thymocyte subpopulations in mice after whole-body X-irradiation.
Oka S, Kubo K, Matsuyama S, Takamori Y. J Vet Med Sci. 1999 Jun;61(6):709-12.
B220 is expressed on apoptotic thymocytes induced by X-irradiation.
Oka S, Kubo K, Matsuyama S, Takamori Y. J Vet Med Sci. 1999 Apr;61(4):337-41.
1998年
Frequent expression of the c-kit proto-oncogene in canine malignant mammary tumor.
Kubo K, Matsuyama S, Katayama K, Tsutsumi C, Yonezawa K, Shimada T, Kotani T, Sakuma S, Ohashi F, Takamori Y. J Vet Med Sci. 1998 Dec;60(12):1335-40.
Induction of fragile sites by fluorodeoxyuridine and caffeine accompanies with misincorpolation of endogenous uridine nucleotide into DNA of feline fibroblasts.
Kubo K, Shiomi A, Asaeda A, Ohashi F, Matsuyama S, Ide H, Takamori Y. J Vet Med Sci. 1998 Dec;60(12):1293-7.
Novel putative fragile sites observed in feline fibroblasts treated with aphidicolin and fluorodeoxyuridine.
Kubo K, Matsuyama S, Sato K, Shiomi A, Ono K, Ito Y, Ohashi F, Takamori Y. J Vet Med Sci. 1998 Jul;60(7):809-13.
1997年
A control of a golden retriever with renal dysplasia.
Miyamoto T, Wakizaka S, Matsuyama S, Baba E, Ohashi F, Kuwamura M, Yamate J, Kotani T. J Vet Med Sci. 1997 Oct 59:939-942.
Enhancement of estrogen receptor gene expression in the mediobasal hypothlamus during anestrus in the beagle bitch.
Tani H, Inaba T, Matsuyama S, Takamori Y, Torii R, Takano H, Tamada H, Sawada T. Neurosci Lett. 1997 Oct 227-149-152.
Purification characterization, and localization of an ADP-ribosylactin hydrolase that uses ADP-ribosylated actin from rat brains as a substrate.
Okamoto H, Fujita F, Matsuyama S, Tsuyama S. J Biol Chem. 1997 Oct 272:28116-28125.
Partial cloning of prohibitin cDNA from canine, feline, bovine, equine, and rabbit liver mRNA by RT-PCR.
Matsuyama S, Kubo K, Ohashi F, Takamori Y. J Vet Med Sci. 1997 Mar;59(3):201-3.
1994年
Targeting the immunoglobulin-binding domain of protein A to the extracellular matrix using a minifibronectin expression vector.
Matsuyama S, Ihihara-Tanaka S, Sekiguchi K. J Biochem. 1994 Jul 116:898-904.
1991年
Mono-ADP-ribosylation in brain: purification and characterization of ADP-ribosyltransferases affecting actin from rat brain.
Matsuyama S, Tsuyama S. J Neurochem. 1991 Sep 57:1380-1387.
1987年
Numerous phosphates of microtubule-associated protein 2 in living rat brain.
Tsuyama S, Terayama Y, Matsuyama S. J Biol Chem. 1987 Aug 262:10886-10892.
