過去の業績一覧

(2016)

Kokoshima H, Yamada N, Doi T, Tsuchitani M, Yamate J
Histopathological and immunohistochemical characterization of spontaneous pituitary tumors in dwarfs derived from Wistar Hannover GALAS rats.
Exp Toxicol Pathol 68(2-3):191-6, 2016. https://doi.org/10.1016/j.etp.2015.11.001. 

Mitori H, Izawa T, Kuwamura M, Matsumoto M, Yamate J
Developing Stage-dependent Retinal Toxicity Induced by l-glutamate in Neonatal Rats.
Toxicol Pathol. 44(8):1137-1145, 2016. https://doi.org/10.1177/0192623316676424.

Shimotsuma Y, Tanaka M, Izawa T, Yamate J, Kuwamura M
Enhanced expression of Trib3 during the development of myelin breakdown in dmy myelin mutant rats.
PLoS One 11(12): e0168250, 2016. https://doi.org/10.1371/journal.pone.0168250.

Harada N, Hanaoka R, Hanada K, Izawa T, Inui H, Yamaji R
Hypogonadism alters cecal and fecal microbiota in male mice.
Gut Microbes 7(6):533-539, 2016. https://doi.org/10.1080/19490976.2016.1239680.

Ogata K, Kushida M, Miyata K, Sumida K, Takeda S, Izawa T, Kuwamura M, Yamate J
Alteration of microRNA expressions in the pons and medulla in rats after 3,3′-iminodipropionitrile administration.
J Toxicol Pathol. 29(4):229-236, 2016. https://doi.org/10.1293/tox.2016-0019. 

Yamate J, Izawa T, Kuwamura M
Histopathological analysis of rat hepatotoxicity based on macrophage functions: in particular, an analysis for thioacetamide-induced hepatic lesions.
Food Safety 3:61-73, 2016. https://doi.org/10.14252/foodsafetyfscj.2016012.

Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, Yamate J
The kinetics of damage-associated molecular patterns (DAMPs) and Toll-like receptors during thioacetamide-induced acute liver injury in rats.
Exp Toxicol Pathol 68(8):471-7, 2016. https://doi.org/10.1016/j.etp.2016.06.005. 

Bondoc A, Katou-Ichikawa C, Golbar HM, Tanaka M, Izawa T, Kuwamura M, Yamate J
Establishment and characterization of a transplantable tumor line (RMM) and cell line (RMM-C) from a malignant amelanotic melanoma in the F344 rat, with particular reference to galectin-3 expresison in vivo and in vitro.
Histol Histopathol 31(11):1195-207, 2016. https://dialnet.unirioja.es/servlet/articulo?codigo=5613424

Pervin M, Izawa T, Ito S, Kuwamura M, Yamate J
Metastatic Liposarcoma in a South African Fur Seal (Arctocephalus pusillus).
J Com Pathol 155(1):72-5, 2016. https://doi.org/10.1016/j.jcpa.2016.05.008.

Nishitani A, Tanaka M, Shimizu S, Yokoe M, Yoshida Y, Suzuki T, Sakuma T, Yamamoto T, Kuwamura M, Takenaka S, Ohno Y, Kuramoto T
Involvement of aspartoacylase in tremor expression in rats.
Exp Anim 65(3):293-301, 2016. https://doi.org/10.1538/expanim.16-0007. 

Minakawa T, Ueda K, Tanaka M, Tanaka N, Kuwamura M, Izawa T, Konno N, Yamate J, Nakagawa Itano E, Sano A, Wada S
Detection of multiple budding yeast cells and a partial sequence of 43-kda glycoprotein coding gene of Paracoccidioides brasiliensis from a case of lacaziosis in a female pacific white-sided dolphin (Lagenorhynchus obliquidens).
Mycopathologia 181(7-8):523-9, 2016. https://link.springer.com/article/10.1007/s11046-016-9988-4.

Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J
M1-/M2-macrophage polarization in pseudolobules consisting of adipophilin-rich hepatocytes in thioacetamide (TAA)-induced rat hepatic cirrhosis.
Exp Mol Pathol 101:133-42, 2016. https://doi.org/10.1016/j.yexmp.2016.07.005.

Katou-Ichikawa C, Izawa T, Sasai H, Kuwamura M, Yamate J
Multiple histiocytic foam cell nodules in the tongue of miniature dachshund dogs.
Vet Pathol 53(3):625-8, 2016. https://doi.org/10.1177/0300985815594850. 

Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J
Transient effects of empty liposomes on hepatic macrophage populations in rats.
J Toxicol Pathol 29(2):139–144, 2016. https://doi.org/10.1293/tox.2015-0082.

Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J
Immunophenotypical characterization and influence on liver homeostasis of depleting and repopulating hepatic macrophages in rats injected with clodronate.
Exp Toxicol Pathol 68(2-3):113-24, 2016. https://doi.org/10.1016/j.etp.2015.11.003. 

Golbar HM, Izawa T, Wijesundera KK, Bondoc A, Tennakoon A, Kuwamura M, Yamate J
Depletion of hepatic macrophages aggravates liver lesion induced in rats by thioacetamide (TAA).
Toxicol Pathol 44(2):246-58, 2016. https://doi.org/10.1177/0192623315621191

Bessho T, Okada T, Kimura C, Shinohara T, Tomiyama A, Imamura A, Kuwamura M, Nishimura K, Fujimori K, Shuto S, Ishibashi O, Kubata BK, Inui T
Novel characteristics of Trypanosoma brucei guanosine 5′-monophosphate reductase distinct from host animals.
PLoS Negl Trop Dis 10(1):e0004339, 2016. https://doi.org/10.1371/journal.pntd.0004339.

Ayata M, Tanaka M, Kameoka K, Kuwamura M, Takeuchi K, Takeda M, Kanou K, Ogura H
Amino acid substitutions in the heptad repeat A and C regions of the F protein responsible for neurovirulence of measles virus Osaka-1 strain from a patient with subacute sclerosing panencephalitis.
Virology 487:141-9, 2016. https://doi.org/10.1016/j.virol.2015.10.004.

Tennakoon AH, Izawa T, Kuwamura M, Yamate J
Pathogenesis of the type 2 of epithelial to mesenchymal transition (EMT) in renal and hepatic fibrosis.
J Clin Med 5(1):4, 2016. https://doi.org/10.3390/jcm5010004.

(2015)

Tennakoon AH, Izawa T, Kuwamura M, Yamate J
Pathogenesis of type 2 epithelial to mesenchymal transition (EMT) in renal and hepatic fibrosis.
J Clin Med 5(1):4, 2015 doi: 10.3390/jcm5010004.

Suzuki Y, Yamaguchi I, Myojo K, Kimoto N, Imaizumi M, Takada C, Sanada H, Takaba K, Yamate J
Histopathological characterization of renal tubular and interstitial changes in 5/6 nephrectomized marmoset monkeys (Callithrix jacchus).
Exp Toxicol Pathol 67(1):41-51, 2015 doi: 10.1016/j.etp.2014.09.007.

Sasai H, Fujita D, Tagami Y, Seto E, Denda Y, Hamakita H, Ichihashi T, Okamura K, Furuya M, Tani H, Sasai K, Yamate J
Characteristics of bone fractures and usefulness of micro-computed tomography for fracture detection in rabbits: 210 cases (2007-2013).
J Am Vet Med Assoc 246(12):1339-44, 2015 doi: 10.2460/javma.246.12.1339.

Nishimura Y, Kondo C, Morikawa Y, Tonomura Y, Torii M, Yamate J, Uehara T
Plasma miR-208 as a useful biomarker for drug-induced cardiotoxicity in rats.
J Appl Toxicol 35(2):173-80, 2015 doi: 10.1002/jat.3044.

Matsuo Y, Azuma YT, Kuwamura M, Kuramoto N, Nishiyama K, Yoshida N, Ikeda Y, Fujimoto Y, Nakajima H, Takeuchi T
Interleukin 19 reduces inflammation in chemically induced experimental colitis.
Int Immunopharmacol 29(2):468-75, 2015 doi: 10.1016/j.intimp.2015.10.011.

Kuramoto T, Yokoe M, Tanaka D, Yuri A, Nishitani A, Higuchi Y, Yoshimi K,
Tanaka M, Kuwamura M, Hiai H, Kabashima K, Serikawa T
Atopic dermatitis-like skin lesions with IgE hyperproduction and pruritus in KFRS4/Kyo rats.
J Dermatol Sci 80(2):116-23, 2015 doi: 10.1016/j.jdermsci.2015.09.005.

Kotera T, Ichikawa-Katou C, Tennakoon A, Tanaka M, Tanaka N, Izawa T, Kuwamura M, Ochi S, Yamate J
Rat malignant fibrous histiocytoma (MFH)-derived cloned cell lines (MT-8 and MT-9) show different differentiation in mesenchymal stem cell lineage.
Exp Toxicol Pathol 67(10):499-507, 2015 doi: 10.1016/j.etp.2015.07.004.

Anayama H, Fukuda R, and Yamate J
Adipose progenitor cells reside among the mature adipocytes: Morphological research using an organotypic culture system.
Cell Biology International 39(11):1288-98, 2015 doi: 10.1002/cbin.10503.

Itakura M, Nakajima H, Kubo T, Semi Y, Kume S, Higashida S, Kaneshige A, Kuwamura M, Harada N, Kita A, Azuma YT, Yamaji R, Inui T, Takeuchi T
Glyceraldehyde-3-Phosphate Dehydrogenase Aggregates Accelerate Amyloid-βAmyloidogenesis in Alzheimer Disease.
J Biol Chem 290(43):26072-87, 2015 doi: 10.1074/jbc.M115.669291.

Yuba E, Kanda Y, Yoshizaki Y, Teranishi R, Harada A, Sugiura K, Izawa T, Yamate J, Sakaguchi N, Koiwai K, Kono K
pH-sensitive polymer-liposome-based antigen delivery systems potentiated with interferon-γ gene lipoplex for efficient cancer immunotherapy.
Biomaterials 67:214-24, 2015 doi: 10.1016/j.biomaterials.2015.07.031.

Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J
M1-/M2-macrophages contribute to the development of GST-P-positive preneoplastic lesions in chemically-induced rat cirrhosis.
Exp Toxicol Pathol 67(9):467-75, 2015 doi: 10.1016/j.etp.2015.05.002.

Kuramochi M, Izawa T, Hori M, Kusuda K, Shimizu J, Iseri T, Akiyoshi H, Ohashi F, Kuwamura M, Yamate J
Chordoma of the thoracic vertebrae in a Bengal tiger (Panthera tigris tigris).
J Vet Med Sci 77(7):893-5, 2015 doi: 10.1292/jvms.14-0658.

Iseri T, Shimizu J, Akiyoshi H, Kusuda K, Hayashi A, Mie K, Izawa T, Kuwamura M, Yamate J, Fujimoto Y, Ohashi F
Computed tomography and magnetic resonance imaging of thoracic chordoma in a Bengal tiger (Panthera tigris tigris).
J Vet Med Sci 77(7):857-60, 2015 doi: 10.1292/jvms.14-0694.

Izawa T, Horiuchi T, Atarashi M, Kuwamura M, Yamate J
Anti-fibrotic role of miR-214 in thioacetamide-induced liver cirrhosis in rats.
Toxicol Pathol 43(6):844-51, 2015 doi: 10.1177/0192623315573587.

Tanaka N, Izawa T, Takenaka S, Yamate J, Kuwamura M
Ccdc85C, a causative protein for hydrocephalus and subcortical heterotopia, is expressed in the systemic epithelia with proliferative activity in rats
Histol Histopathol 30(7):823-32, 201 doi: 10.14670/HH-11-589.

Harada N, Katsuki T, Takahashi Y, Masuda T, Yoshinaga M, Adachi T, Izawa T, Kuwamura M, Nakano Y, Yamaji R, Inui H
Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-cells.
J Cell Biochem 116(6):998-1006, 2015 doi: 10.1002/jcb.25054.

Tennakoon AH, Izawa T, Wijesundera KK, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J
Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA).
Exp Mol Pathol 98:476-85, 2015 doi: 10.1016/j.yexmp.2015.03.010.

Ogata K, Sumida K, Miyata K, Kushida M, Kuwamura M, Yamate J
Circulating miR-9 abd miR-384-5p as potential indicators for trimethyltin-induced neurotoxicity.
Toxicol Pathol 43(2):198-208, 2015 doi: 10.1177/0192623314530533.

Yano R, Golbar HM, Izawa T, Sawamoto O, Kuwamura M, Yamate J
Participation of bone morphogenetic protein (BMP)-6 and osteopontin in cisplatin (CDDP)-induced rat renal fibrosis.
Exp Toxicol Pathol 67(2):99-107, 2015 doi: 10.1016/j.etp.2014.10.002.

Tennakoon AH, Izawa T, Wijesundera KK, Murakami H, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J
Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA).
Exp Toxicol Pathol 67(1):53-63, 2015 doi: 10.1016/j.etp.2014.09.008.

(2014)

Yamaguchi I, Myojo K, Sanada H, Takami A, Suzuki Y, Imaizumi M, Takada C, Kimoto N, Saeki K, Yamate J, Takaba
Five-sixth nephrectomy in female common marmosets(Callithrix jacchus) as a chronic renal failure model: -A longitudinal course of serum biochemical, hematological and histopathological changes-.
J Toxicol Pathol 27(3-4):183-95, 2014 doi: 10.1293/tox.2013-0055.

Uehara T, Horinouchi A, Morikawa Y, Tonomura Y, Minami K, Ono A, Yamate J, Yamada H, Ohno Y, Urushidani T
Identification of metabolomic biomarkers for drug-induced acute kidney injury in rats.
J Appl Toxicol 34(10):1087-95, 2014 doi: 10.1002/jat.2933.

Motoyoshi-Yamashiro A, Takano K, Kawabe K, Izawa T, Nakajima H, Nakamura Y
Amphotericin B induces glial cell line-derived neurotrophic factor in rat brain.
J Vet Med Sci 76(10):1353-8, 2014  doi: 10.1292/jvms.14-0160.

Yamate J, Gamou K, Izawa-Ogata K, Kotera T, Izawa T, Takenaka S, Sawamoto O, Kuwamura M.
Characterization of rat testicular teratoma and its derived cell lines, with particular reference to possible mesenchymal differentiations.
Histol Histopathol 29(9):1201-16, 2014 doi: 10.14670/HH-29.1201.

Tanaka M, Izawa T, Yamate J, Franklin RJM, Kuramoto T, Serikawa T, Kuwamura M
The VF rat with abnormal myelinogenesis has a mutation in Dopey1.
Glia 62(9):1530-42, 2014 doi: 10.1002/glia.22698.

Kashiwagi E, Tonomura Y, Kondo C, Masuno K, Fujisawa K, Tsuchiya N, Matsushima S, Torii M, Takasu N, Izawa T, Kuwamura M, Yamate J.
Involvement of neutrophil gelatinase-associated lipocalin and osteopontin in renal tubular regeneration and interstitial fibrosis after cisplatin-induced renal failure.
Exp Toxicol Pathol 66(7):301-11, 2014 doi: 10.1016/j.etp.2014.04.007.

Golbar HM, Izawa T, Wijesundera KK, Tennakoon AH, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
Expression of nestin in remodelling of α-naphthylisothiocyanate-induced acute bile duct injury in rats.
J Comp Pathol 151(2-3):255-63, 2014 doi: 10.1016/j.jcpa.2014.05.003.

Bondoc A, Izawa T, Hirata S, Hasegawa T, Kuwamura M, Golbar HM, Yamate J
Myoepihtelioma of the gland of the third eyelid in a dog.
J Comp Pathol 151(2-3):186-9, 2014 doi: 10.1016/j.jcpa.2014.04.011.

Golbar HM, Izawa T, Kuwamura M, Fujita D, Sasai H, Yamate J
A collision tumour consisting of malignant trichoblastoma and melanosarcoma in a rabbit.
J Comp Pathol 151(1):63-6, 2014 doi: 10.1016/j.jcpa.2014.03.002.

Yuasa T, Yano R, Izawa T, Kuwamura M, Yamate J
Calponin expression in renal tubuolointerstitial fibrosis induced in rats by cisplatin.
J Toxicol Pathol 27(1):97-103, 2014 doi: 10.1293/tox.2013-0048.

Wijesundera KK, Izawa T, Tennakoon AH, Murakami H, Golbar HM, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-3
Exp Mol Pathol 96(3):382-92, 2014 doi: 10.1016/j.yexmp.2014.04.003.

Wijesundera KK, Izawa T, Murakami H, Tennakoon AH, Golbar HM, Kato-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions: a possible analysis for hepto-pathology.
Histol Histopathol 29(4):497-511, 2014 doi: 10.14670/HH-29.10.497.

Tanaka N, Izawa T, Kuwamura M, Higashiguchi N, Kezuka C, Yamate J
Pheochromocytoma and hepatocellular carcinoma with nuclear glycogenation of the hepatocytes in a predatory carp, Chanodichthys erthropterus (Basilewsky).
J Fish Dis 37(4):411-4, 2014 doi: 10.1111/jfd.12137.

Tanaka N, Izawa T, Kuwamura M, Higashiguchi N, Kezuka C, Kurata O, Wada S, Yamate J
The first case of infectious spleen and kidney necrosis virus (ISKNV) infection in aquarium-maintained mandarin fish, Siniperca chuatsi (Basilewsky), in Japan.
J Fish Dis 37(4):401-5, 2014 doi: 10.1111/jfd.12134.

Nishida H, Nakayama M, Tanaka H, Kamishina H, Izawa T, Hatoya S, Sugiura K, Suzuki Y, Ide C, Inaba T
Evaluation of serum phosphorylated neurofilament subunit NF-H as a prognostic biomerker in dogs with thoracolumbar intervertebral disc hermiation.
Vet Surg 43(3):289-93, 2014 doi: 10.1111/j.1532-950X.2014.12144.x.

Izawa T, Murakami H, Wijesundera KK, Golbar HM, Kuwamura M, Yamate J
Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats.
Exp Toxicol Pathol 66(2-3):155-62, 2014 doi: 10.1016/j.etp.2013.12.002.

Kasamoto S, Mukai D, Masumori S, Suzuki K, Tanaka R, Torous DK, Yamate J, Hayahsi M
Flow cytometric analysis of micronuclei in rat peripheral blood: an interlaboratory reproducibility study.
Mutat Res 762:39-42, 2014 doi: 10.1016/j.mrgentox.2014.02.001.

Tanaka M, Izawa T, Kuwamura M, Ozaki M, Nakao T, Ito S, Yamate J
A case of meconium aspiration syndrome in a Bottlenose Dophin (Tursiops truncatus) Calf.
J Vet Med Sci 76(1):81-4, 2014 doi: 10.1292/jvms.13-0227.

(2013)

Taketa Y, Inoue K, Takahashi M, Yamate J, Yoshida M
Differential morphological effects in rat corpora lutea among ethylene glycol monomethyl ether, atrazine, and bromocriptine.
Toxicol Pathol 41(5):736-43, 2013 doi: 10.1177/0192623312464305.

Suzuki Y, Yamaguchi I, Onoda N, Saito T, Myojo K, Imaizumi M, Takada C, Kimoto N, Takaba K, Yamate J
Differential renal glomerular changes induced by 5/6 nephrectomization between common marmoset monkeys (Callithrix jacchus) and rats.
Exp Toxicol Pathol 65(5):667-76, 2013 doi: 10.1016/j.etp.2012.08.001.

Mecklenburg L, Kusewitt D, Kolly C, Treumann S, Adams ET, Diegel K, Yamate J, Kaufmann W, Müller S, Danilenko D, Bradley A
Proliferative and non-proliferative lesions of the rat and mouse integument.
J Toxicol Pathol 26(3 Suppl):27S-57S, 2013 doi: 10.1293/tox.26.27S.

Gal A, Yamate J, Golbar HM, Spoerer K, Fredrickson R.
Littoral cell angiosarcoma in a dog.
J Comp Pathol 149(2-3):221-4, 2013 doi: 10.1016/j.jcpa.2013.01.003.

Awasthi SP, Asakura M, Chowdhury N, Neogi SB, Hinenoya A, Golbar HM, Yamate J, Arakawa E, Tada T, Ramamurthy T, Yamasaki S
Novel cholix toxin variants, ADP-ribosylating toxins in Vibrio cholerae non-O1/non-O139 strains, and their pathogenicity.
Infect Immun 81(2):531-41, 2013 doi: 10.1128/IAI.00982-12.

Tanaka N, Izawa T, Kashiwagi-Yamamoto E, Kuwamura M, Ozaki M, Nakao T, Yamate J
Primary cerebral T-cell lymphoma in a sea otter (Enhydra lutris)
J Vet Med Sci 75(12):1667-9, 2013 doi: 10.1292/jvms.13-0331.

Tennakoon AH, Izawa T, Wijesundera KK, Golbar HM, Tanaka M, Ichikawa C, Kuwamura M, Yamate J
Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury.
Exp Toxicol Pathol 64(7-8):1159-71, 2013 doi: 10.1016/j.etp.2013.05.008.

Tennakoon AH, Izawa T, Fujita D, Denda Y, Seto E, Sasai H, Kuwamura M, Yamate J
Combined hepatocellular-cholangiocarcinoma in a yellow-headed amazon (Amazon aoratrix).
J Vet Med Sci 75(11):1507-10, 2013 doi: 10.1292/jvms.13-0192.

Tanaka T, Shimada T, Akiyoshi H, Shimizu J, Zheng C, Yiyun L, Mie K, Hayashi A, Kuwamura M, Hoshi F, Ohashi F
Relationship between major histocompatibility complex class I expression and prognosis in canine mammary gland tumors.
J Vet Med Sci 75(10):1393-8, 2013 doi: 10.1292/jvms.13-0080.

Wijesundera KK, Juniantito V, Golbar HM, Fujisawa K, Tanaka M, Ichikawa C, Izawa T, Kuwamura M, Yamate J
Expressions of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions.
Exp Toxicol Pathol 65(6):799-808, 2013 doi: 10.1016/j.etp.2012.11.006.

Wijesundera KK, Izawa T, Fujita D, Denda Y, Seto E, Sasai H, Kuwamura M, Yamate J
Spontaneous extraskeletal osteosarcoma in a rabbit (Oryctolagus cuniculus) : histopathological and immunohistochemical findings.
J Toxicol Pathol 26(3):309-12, 2013 doi: 10.1293/tox.26.309.

Ueda K, Sano A, Yamate J, Itano E, Kuwamura M, Izawa T, Tanaka M, Hasegawa Y, Chibana H, Izumisawa Y, Miyahara H, Uchida S
Two cases of lacaziosis in bottlenose dolphins (Tursiops truncates) in Japan
Case Report Vet Med, Article ID 318548, 2013

Golbar HM, Izawa T, Ichikawa C, Tanaka M, Juniantito V, Sawamoto O, Kuwamura M, Yamate J
Slowly progressive cholangiofibrosis induced in rats byα-naphthylisothiocyanate (ANIT), with particular references to characteristics of macrophages and myofibroblasts.
Exp Toxicol Pathol 65(6):825-35, 2013 doi: 10.1016/j.etp.2012.12.001.

Yamamoto R, Akiyoshi H, Hukui H, Hirata S, Izawa T, Ohashi F, Kubo K
A case of canine seminoma that metastasized to a medial iliac lymph node and was treated with preoperative irradiation and surgical resection.
J Jpn Vet Med Assoc 66:553-6, 2013

Yuasa T, Juniantito V, Ichikawa C, Yano R, Izawa T, Kuwamura M, Yamate J
Thy-1 expression, a possible marker of early myofibroblast development, in renal tubulointerstitial fibrosis induced in rats by cisplatin.
Exp Toxicol Pathol 65(5):651-9, 2013 doi: 10.1016/j.etp.2012.07.005.

Nishimura T, Hatoya S, Kanegi R, Sugiura K, Wijewardana V, Kuwamura M, Tanaka M, Yamate J, Izawa T, Takahashi M, Kawate N, Tamada H, Imai H, Inaba T
Generation of functional platelets from canine induced pluripotent stem cells
Stem Cells Dev 22(14):2026-35, 2013 doi: 10.1089/scd.2012.0701.

Juniantito V, Izawa T, Yuasa T, Ichikawa C, Tanaka M, Kuwamura M, Yamate J
Immunophenotypical analysis of myofibroblasts and mesenchymal cells in the bleomycin-induced rat scleroderma, with particular reference to their origin.
Exp Toxicol Pathol 65(5):567-77, 2013 doi: 10.1016/j.etp.2012.05.002.

Golbar HM, Izawa T, Juniantito V, Ichikawa C, Tanaka M, Kuwamura M, Yamate J
Imuunohistochemical characterization of macrophages and myofibroblasts in fibrotic liver lesions due to Fasciola infection in cattle.
J Vet Med Sci 75(7):857-65, 2013 doi: 10.1292/jvms.12-0536.

Fujisawa K, Yabuuchi C, Izawa T, Kuwamura M, Takasu N, Torii M, Yamate J.
Expression patterns of heat shock protein 25 in carbon tetrachloride-induced rat liver injury.
Exp Toxicol Pathol 65(5):469-76, 2013 doi: 10.1016/j.etp.2012.02.001.

Hori M, Juniantito V, Izawa T, Ichikawa C, Tanaka M, Tanaka K, Takenaka S, Kuwamura M, Yamate J
Distribution of cells labelled by a novel somatic stem cell-recognizing antibody (A3) in pulmonary genesis and bleomycin-induced pulmonary fibrosis in rats.
J Comp Pathol 148(4):385-95, 2013 doi: 10.1016/j.jcpa.2012.09.003.

Wijesundera KK, Izawa T, Tanaka M, Kuwamura M, Yamate J
Pulmonary dystrophic oxalosis and its possible relation to fibrosis in an aged Gentoo Penguin (Pygoscelis papua).
J Vet Med Sci 75(3):365-8, 2013 doi: 10.1292/jvms.12-0342.

Uehara T, Ainslie GR, Kutanzi K, Pogribny IP, Mushkelishvili L, Izawa T, Yamate J, kosyk O, Shymonyak S, Bradford BU, Boorman GA, Bataller R, Rusyn I
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis.
Toxicol Sci 132(1):53-63, 2013 doi: 10.1093/toxsci/kfs342.

Ichikawa C, Izawa T, Juniantio V, Tanaka M, Hori M, Tanaka K, Takenaka S, Kuwamura M, Yamate J
Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development
Histol Histopathol 28(2):257-68, 2013 doi: 10.14670/HH-28.257.

Juniantito V, Izawa T, Yuasa T, Ichikawa C, Yano R, Kuwamura M, Yamate J
Immunophenotypical characterization of macrophages in rat bleomycin-induced scleroderma
Vet Pathol 50(1):76-85, 2013 doi: 10.1177/0300985812450718.

Uehara T, Kondo C, Morikawa Y, Hanafusa H, Ueda S, Minowa Y, Nakatsu N, Ono A, Maruyama T, Kato I, Yamate J, Yamada H, Ohno Y, Urushidani T.
Toxicogenomic biomarkers for renal papillary injury in rats.
Toxicology 303:1-8, 2013 doi: 10.1016/j.tox.2012.09.012.

(2012)

Tanaka M, Soma K, Izawa T, Yamate J, Franklin RJM, Kuramoto T, Serikawa T, Kuwamura M
Abnormal myelinogenesis in the central nervous system of the VF mutant rat with recoverable tremor.
Brain Res 1488:104-12, 2012 doi: 10.1016/j.brainres.2012.09.037. 

Izawa T, Tanaka M, Aoki M, Ohashi F, Yamate J, Kuwamura M
Incidental synovial myxoma with extensive intermuscular infiltration in a dog.
J Vet Med Sci 74(12):1631-3, 2012 doi: 10.1292/jvms.12-0207.

Uddin MM, Tanimoto T, Yabuki A, Kotani T, Kuwamura M, Chang HS, Osamu Yamato O.
Mutation analysis of GM1 gangliosidosis in a Siamese cat from Japan in the 1960s.
J Feline Med Surg 14(12):900-2, 2012 doi: 10.1177/1098612X12454120.

Furusawa Y, Mizukami K, Yabuki A, Kuwamura M, Chang HS, Hossain MA, Rahman MM, Uddin MM, Mitani S, Yamato O.
Mutational analysis of the feline CLN3 gene and an ultrastructural evaluation of lysosomal storage materials in a cat with neuronal ceroid lipofuscinosis: An investigation into the molecular basis of the disease.
Vet J 194(3):425-8, 2012 doi: 10.1016/j.tvjl.2012.04.025.

Nishida H, Shoji Y, Nakamura M, Hatoya S, Sugiura K, Yamate J, Kuwamura M, Kotani T, Nakayama M, Suzuki Y, Ide C, Inaba T
Evaluation of methods for cell harvesting and the biological properties at successive passages of canine bone marrow stromal cells.
Am J Vet Res 73(11):1832-40, 2012 doi: 10.2460/ajvr.73.11.1832.

Taketa Y, Yoshida M, Inoue K, Takahashi M, Sakamoto Y, Watanabe G, Taya K, Yamate J, Nishikawa A.
The newly formed corpora lutea of normal cycling rats exhibit drastic changes in steroidogenic and luteolytic gene expressions.
Exp Toxicol Pathol 64(7-8):775-82, 2012 doi: 10.1016/j.etp.2011.01.015.

Yamamoto E, Izawa T, Sawamoto O, Juniantito V, Kuwamura M, Yamate J
Amelioration of cisplatin-induced rat renal lesions by a cyclooxygenase (COX)-2 selective inhibitor.
Exp Toxicol Pathol 64:625-31, 2012 doi: 10.1016/j.etp.2010.12.005.

Baulac S, Ishida S, Mashimo T, Boillot M, Fumoto N, Kuwamura M, Ohno Y, Takizawa A, Aoto T, Ueda M, Ikeda A, LeGuern E, Takahashi R, Serikawa T
A rat mode for LGI1-related epilepsies.
Hum Mol Genet 21(16):3546-57, 2012

Kondo C, Aoki M, Yamamot E, Tonomura Y, Ikeda M, Kaneto M, Yamate J, Torii M, Uehara T
Predictive genomic biomarkers for drug-induced nephrotoxicity in mice.
J Toxicol Sci 37:723-37, 2012 doi: 10.2131/jts.37.723.

Tanaka M, Izawa T, Kuwamura M, Nakao T, Maezono Y, Ito S, Murata M, Murakami M, Sano A, Yamate J
Deep granulomatous dermatitis of the fin caused by fusarium salani in a false killer whale (Pseudorca crassidens).
J Vet Med Sci 74(6):779-82, 2012 doi: 10.1292/jvms.11-0421.

Kobayashi K, Izawa T, Kuwamura M, Yamate J
Dysferlin and animal models for dysferlinopathy.
J Toxicol Pathol 25(2): 135-147, 2012 doi: 10.1293/tox.25.135.

Minowa Y, Kondo C, Uehara T, Morikawa Y, Okuno Y, Nakatsu N, Ono A, Maruyama T, Kato I, Yamate J, Yamada H, Ohno Y, Urushidani T
Toxicogenomic multigene biomarker for predicting the future onset of proximal tubular injury in rats.
Toxicology 297:47-56, 2012 doi: 10.1016/j.tox.2012.03.014.

Juniantito V, Izawa T, Yuasa T, Ichikawa C, Yamamoto E, Kuwamura M, Yamate J
Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts
Histol Histopathol 27(4):515-27, 2012 doi: 10.14670/HH-27.515.

Ishida S, Sakamoto Y, Nishio T, Baulac S, Kuwamura M, Ohno Y, Takizawa A, Kaneko S, Serikawa T, Mashimo T
Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
Brain Res 1435:154-66, 2012 doi: 10.1016/j.brainres.2011.11.023.

Mori N#, Kuwamura M#, Tanaka N, Hirano R, Nabe M, Ibuki M, Yamate J
Ccdc85c encoding a protein at apical junction of radial glia is disrupted in hemorrhagic hydrocephalus hhy mice.
Am J Pathol 180(1):314-27, 2012 doi: 10.1016/j.ajpath.2011.09.014. 
#:contributed equally

Nakajima H, Kubo T, Semi Y, Itakura M, Kuwamura M, Izawa T, Azuma YT, Takeuchi T
A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain.
J Biotechnol 157(2):326-33, 2012 doi: 10.1016/j.jbiotec.2011.10.003.

Glober HM, Izawa T, Murai F, Kuwamura M, Yamate J
Immunohistochemical analyses of the kinetics and distribution of macrophages, hepatic stelate cells and bile duct epithelia in the developing rat liver.
Exp Toxicol Pathol 64(1-2):1-8, 2012 doi: 10.1016/j.etp.2010.05.011.

(2011)

Yamamoto E, Izawa T, Kuwamura M, Yamate J
Immunohistochemical expressions of main PGE2 biosynthesis-related enzymes
and PGE2 receptor in rat nephrogenesis
J Toxicol Pathol 24(4):257-61, 2011 doi: 10.1293/tox.24.257.

Golbar HM, Izawa T, Yano R, Kuwamura M, Okamura K, Fujita D, Tagami Y, Sasai H, Yamate J
A collision tumor consisting of granular cell tumor and adenocarcinoma in the uterus of an aged djungarian hamster.
J Toxicol Pathol 24(4):233-7, 2011 doi: 10.1293/tox.24.233.

Juniantito V, Izawa T, Yamamoto E, Murai F, Kuwamura M, Yamate J
Heterogeneity of macrophage populations and expression of galectin-3 in cutaneous wound healing in rats.
J Comp Pathol 145(4):378-89, 2011 doi: 10.1016/j.jcpa.2011.01.012.

Yamate J, Murai F, Izawa T, Akiyoshi H, Shimizu J, Ohashi F, Kuwamura M
A rhabdomyosarcoma arising in the larynx of a dog
J Toxicol Pathol 24(3):179-82, 201 doi: 10.1293/tox.24.179.

Uehara T, Yamate J, Torii M, Maruyama T
Comparative nephrotoxicity of Cisplatin and nedaplatin: mechanisms and histopathological characteristics.
J Toxicol Pathol 24(2):87-94, 2011 doi: 10.1293/tox.24.87.

Golbar HM, Izawa T, Kuwamura M, Fujita D, Okamura K, Yamazaki R, Tagami Y, Sasai H, Yamate J
Cardiac hamartoma in a young squirrel monkey who died suddenly.
Vet Pathol 48:970-4, 2011 doi: 10.1177/0300985810386466.

Fujisawa K, Miyoshi T, Tonomura Y, Izawa T, Kuwamura M, Torii M, Yamate J
Relatioship of heat shock protein 25 with reactive macrophages in thioacetamide-induced rat liver injury.
Exp Toxicol Pathol 63(6):599-605, 2011 doi: 10.1016/j.etp.2010.04.014.

Golbar HM, Izawa T, Yano R, Ichikawa C, Sawamoto O, Kuwamura M, LaMarre J, Yamate J
Immunohistochemical characteization of macrophages and myofibroblasts in α-naphthylisothiocyanate (ANIT)-induced bile duct injury and subsequent fubrogenesis in rats.
Toxicol Pathol 39(5):795-808, 2011 doi: 10.1177/0192623311413790.

Taketa Y, Yoshida M, Inoue K, Takahashi M, Sakamoto Y, Watanabe G, Taya K, Yamate J, Nishikawa A.
Differential stimulation pathways of progesterone secretion from newly formed corpora lutea in rats treated with ethylene glycol monomethyl ether, sulpiride, or atrazine.
Toxicol Sci 121(2):267-78, 2011 doi: 10.1093/toxsci/kfr062.

Kuwamura M, Inumaki K, Tanaka M, Shirai M, Izawa T, Yamate J, Franklin RJM, Kuramoto T, Serikawa T
Oligodendroglial pathology in the development of myelin breakdown in the dmy murant rat.
Brain Res 1389:161-8, 2011 doi: 10.1016/j.brainres.2011.03.009.

Izawa T, Murai F, Akiyoshi H, Ohashi F, Yamate J, Kuwamura M
Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog.
J Vet Med Sci 73:697-700, 2011 doi: 10.1292/jvms.10-0503.

Kobayashi K, Izawa T, Kuwamura M, Yamate J.
Comparative Gene Expression Analysis in the Skeletal Muscles of Dysferlin-deficient SJL/J and A/J Mice.
J Toxicol Pathol 24(1):49-62, 2011 doi: 10.1293/tox.24.49.

Hatoya S, Kumagai D, Takeda S, Yamamoto E, Nakanishi M, Kuwamura M, Sugiura K, Sasai H, Yamate J, Inaba T
Successful management with CHOP for pulmonary lymphomatoid granulomatosis in a dog.
J Vet Med Sci 73:527-30, 2011 doi: 10.1292/jvms.10-0301.

Uehara T, Kondo C, Yamate J, Torii M, Maruyama T.
A toxicogenomic approach for identifying biomarkers for myelosuppressive anemia in rats.
Toxicology 282(3):139-45, 2011

Taketa Y, Inomata A, Hosokawa S, Sonoda J, Hayakawa K, Nakano K, Momozawa Y, Yamate J, Yoshida M, Aoki T, Tsukidate K.
Histopathological characteristics of luteal hypertrophy induced by ethylene glycol monomethyl ether with a comparison to normal luteal morphology in rats.
Toxicol Pathol 39(2):372-80, 2011 doi: 10.1177/0192623310388429.

Kuramoto T, Kuwamura M, Tokuda S, Izawa T, Nakane Y, Kitada K, Akao M, Guenet JL, Serikawa T
A mutation in the gene encoding mitochondria Mg2+ channel MRS2 results in demyelination in the rat.
PLoS Genetics 7(1):e1001262, 2011 doi: 10.1371/journal.pgen.1001262.

Kuramoto T, Kuwamura M, Tagami F, Mashimo T, Nose M, Serikawa T
Kyoto rhino rat developed through ENU mutagenesis shows congenital hair loss and focal glomerulosclerosis.
Exp Anim 60:57-63, 2011 doi: 10.1538/expanim.60.57.

(2010)

Yamamoto E, Izawa T, Juniantito V, Kuwamura M, Yamate J.
Relationship of Cell Proliferating Marker Expressions with PGE(2) Receptors in Regenerating Rat Renal Tubules after Cisplatin Injection.
J Toxicol Pathol 23(4): 271-275, 2010 doi: 10.1293/tox.23.271.

Ayate M, Takeuchi K, Takeda M, Ohgimoto S, Kato S, Sharma LB, Tanaka M, Kuwamura M, Ishida H, Ogura H
The F gene of the Osaka-2 strain of measles virus derived from subacute sclerosing panencephalitis is a major determinant of neurovirulence.
J Virol 84: 11189-11199, 2010 doi: 10.1128/JVI.01075-10.

Kobayashi K, Izawa T, Kuwamura M, Yamate J
The distribution and characterization of skeletal muscle lesions in dysferlin-deficient SJL and A/J Mice
Exp Toxicol Pathol 62: 509-517, 2010 doi: 10.1016/j.etp.2009.06.009.

Mito K, Sugiura K, Ueda K, Hori T, Akazawa T, Yamate J, Nakagawa H, Hatoya S, Inaba M, Inoue N, Ikehara S, Inaba T.
IFN{gamma} markedly cooperates with intratumoral dendritic cell vaccine in dog tumor models.
Cancer Res 70(18): 7093-7101, 2010 doi: 10.1158/0008-5472.CAN-10-0600.

Azuma Y, Nishiyama K, Matsuo Y, Kuwamura M, Morioka A, Nakajima H, Takeuchi T
PPARalpha contributes to colonic protection in mice with DSS-induced colitis.
Int Immunopharmacol 10: 1261-1267, 2010 doi: 10.1016/j.intimp.2010.07.007.

Yamamoto E, Izawa T, Juniantito V, Kuwamura M, Sugiura K, Takeuchi T, Yamate J
Involvement of endogenous prostaglandin E2 in tubular epithelial regeneration through inhibition of apoptosis and epithelial-mesenchymal transition in cisplatin-induced rat renal lesions
Histol Histopathol 25: 995-1007, 2010 doi: 10.14670/HH-25.995.

Juniantito V, Izawa T, Yamamoto E, Kuwamura M, Yamate J.
The kinetics and distribution of different macrophage populations in the developing rat skin.
Histol Histopathol 25: 985-994, 2010 doi: 10.14670/HH-25.985.

Izawa T, Yamate J, Franklin RJM, Kuwamura M
Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat.
Brain Res 1349: 105-114, 2010 doi: 10.1016/j.brainres.2010.06.030.

Kuramoto T, Hirano R, Kuwamura M, Serikawa T
Identification of the Rex mutation as a 7-bp deletion at splicing acceptor site of the Krt71 gene.
J Vet Med Sci 72: 909-912, 2010 doi: 10.1292/jvms.09-0554.

Azuma YT, Matsuo Y, Kuwamura M, Yancopoulos GD, Valenzuela DM, Murphy AJ, Nakajima H, Karow M, and Takeuchi T
Interleukin-19 protects mice from innate-mediated colonic inflammation.
Inflammatory Bowel Diseases 16: 1017-1028, 2010 doi: 10.1002/ibd.21151.

Hasegawa M, Ide M, Kuwamura M, Yamate J, Takenaka S
Metabolic fingerprinting in toxicological assessment using FT-ICR MS.
J Toxicol Pathol 23(2):67-74. 2010 doi: 10.1293/tox.23.67.

Yuasa T, Izawa T, Kuwamura M, Yamate J
Thy-1 expressing mesenchymal cells in rat nephrogenesis, in correlation with cells immunoreactive for α-smooth muscle actin and vimentin.
J Toxicol Pathol 23: 1-10, 2010 doi: 10.1293/tox.23.1.

Izawa T, Yamate J, Franklin RJM, Kuwamura M
Abnormal myelinogenesis both in the white and gray matter of the attractin-deficient mv rat
Brain Res 1312: 145-155, 2010 doi: 10.1016/j.brainres.2009.11.027.

Golber HM, Izawa T, Kuwamura M, Ito S, Yamate J
Uterine adenocarcinoma with prominent desmoplasia in a geriatric miniature pig.
J Vet Med Sci 72: 253-256, 2010 doi: 10.1292/jvms.09-0372.

(2009)

Sato S, Mukai Y, Yamate J, Norikura T, Morinaga Y, Mikame K, Funaoka M, Fujita S
Lignin-derived lignophenols attenuate oxidative and inflammatory damage to the kidney in streptozotocin-induced diabetic rats.
Free Radic Res 43(12):1205-13, 2009 doi: 10.3109/10715760903247264.

Kondo C, Minowa Y, Uehara T, Okuno Y, Nakatsu N, Ono A, Maruyama T, Kato I, Yamate J, Yamada H, Ohno Y, Urushidani T
Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database.
Toxicology 265: 15-26, 2009 doi: 10.1016/j.tox.2009.09.003.

Juniantito V, Izawa T, Kuwamura M, Yonezawa M, Ito S, Yamate J
Gastrointestinal candidiasis in an Aldabra Giant Tortoise (Geochelone gigantea).
J Vet Med Sci 71: 1269-1272, 2009 doi: 10.1292/jvms.71.1269.

Kuwamura M, Murai F, Nishioka S, Aoki M, Ohashi F, Yamate J, Kotani T, Summers BA
Late onset cerebellar cortical degeneration in a Koala
Aust Vet J 87: 342-344, 2009 doi: 10.1111/j.1751-0813.2009.00463.x.

Kuwamura M, Nakagawa M, Nabe M, Yamate J, Inoue M, Satoh H, Yamato O
Neuronal ceroid-lipofuscinosis in a Japanese domestic shorthair cat.
J Vet Med Sci 71(5): 665-557, 2009 doi: 10.1292/jvms.71.665.

Yamate J, Izawa T, Kuwamura M, Mitsunaga F, Nakamura S
Vasoformative disorder, resembling littoral cell angioma of the spleen in a geriatric Japanese Macaque (Macaca fuscata)
Vet Pathol 46(3): 520-525, 2009 doi: 10.1354/vp.08-VP-0228-Y-CR.

Golbar HM, Izawa T, Kuwamura M, Yonezawa M, Ito S, Yamate J
Malignant seminoma with multiple visceral metastases in a Guinea Fowl (Numida Meleagris) kept in a zoo.
Avian Diseases 53: 143-145, 2009 doi: 10.1637/8460-082808-Case.1.

Mori Y, Izawa T, Takenaka S, Kuwamura M, Yamate J
Participation of functionally different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury.
Toxicol Pathol 37(4): 463-473, 2009 doi: 10.1177/0192623309335634.

Naoi K, Kuramoto T, Kuwamura Y, Gohma H, Kuwamura M, Masuyama T, Serikawa T
Characterization of the Masuyama circling (MCI) rat carrying a spontaneous nonsense mutation in the protocadherin 15 (Pcdh15) gene.
Exp Anim 58 (1): 1-10, 2009 doi: 10.1538/expanim.58.1.

Yamate J, Ishimine S, Izawa T, Kumagai D, Kuwamura M
Macrophage populations and expressions of regulatory proinflammatory factors in the rat meninx under lipopolysaccharide treatment in vivo and in vitro.
Histol Histopathol 24: 13-24, 2009 doi: 10.14670/HH-24.13.

(2008)

Uehara T, Tsuchiya N, Masuda A, Torii M, Nakamura M, Yamate J, Maruyama T
Time course of the change and amelioration of nedaplatin-induced nephrotoxicity in rats.
J Appl Toxicol 28(3):388-98, 2008 doi: 10.1002/jat.1292.

Nishimura K, Sakakibara S, Mitani K, Yamate J, Ohnishi Y, Yamasaki S
Inhibition of interleukin-12 production by Trypanosoma brucei in rat macrophages.
J Parasitol 94(1):99-106, 2008 doi: 10.1645/GE-1322.1.

Izawa T, Yamate J, Takeda S, Kumagai D, Kuwamura M
Cutaneous rhabdoid tumor in a cat.
Vet Pathol 45: 897-900, 2008 doi: 10.1354/vp.45-6-897.

Kuwamura M, Okajima R, Yamate J, Kotani T, Kuramoto T, Serikawa T
Pancreatic metaplasia in the gastro-achlorhydria in WTC-dfk rat, a potassium channel kcnq1 mutant
Vet Pathol 45: 586-591, 2008 doi: 10.1354/vp.45-4-586.

Kannan-Hayashi Y, Okamura K, Hattori S, Kuwamura M, Higuchi E, Terayama H, Moriyama M, Mukamoto M, Okada M, Ohsugi Y, Nakamura Y.
Neuritogenic effects of T Cell-derived IL-3 on mouse splenic sympathetic neurons in vivo.
J Immunol 180(6):4227-34, 2008 doi: 10.4049/jimmunol.180.6.4227.

Izawa T, Takenaka S, Ihara H, Kotani T, Yamate J, Franklin RJM, Kuwamura M
Cellular responses in the spinal cord during development of hypomyelination in the mv rat.
Brain Res 1195: 120-129, 2008 doi: 10.1016/j.brainres.2007.12.022.

Azuma YT, Hagi K, Shintani N, Kuwamura M, Nakajima H, Hashimoto H, Baba A, Takeuchi T.
PACAP provides colonic protection against dextran sodium sulfate induced colitis.
J Cell Physiol 216: 111-9, 2008 doi: 10.1002/jcp.21381.

Sato S, Mukai Y, Yamate J, Kato J, Kurasaki M, Hatai A, Sagai M.
Effect of polyphenol-containing azuki bean (Vigna angularis) extract on blood pressure elevation and macrophage infiltration in the heart and kidney of spontaneously hypertensive rats.
Clin Exp Pharmacol Physiol 35(1):43-9, 2008 doi: 10.1111/j.1440-1681.2007.04743.x.

(2007)

Uehara T, Miyoshi T, Tsuchiya N, Masuno K, Okada M, Inoue S, Torii M, Yamate J, Maruyama T.
Comparative analysis of gene expression between renal cortex and papilla in nedaplatin-induced nephrotoxicity in rats.
Hum Exp Toxicol 26(10):767-80, 2007 doi: 10.1177/0960327107084069.

Hasegawa M, Ide M, Takenaka S, Yamate J, Tsuyama S.
Urinary metabolic fingerprinting for thioacetamide-induced rat acute hepatic injury using fourier transform-ion cyclotron resonance mass spectrometry (FT-ICR MS), with reference to detection of potential biomarkers for hepatotoxicity.
Toxicol Pathol 35(4):570-5, 2007

Uehara T, Tsuchiya N, Masuda A, Torii M, Nakamura M, Yamate J, Maruyama T.
Time course of the change and amelioration of nedaplatin-induced nephrotoxicity in rats.
J Appl Toxicol 8,2007 doi: 10.1002/jat.1292.

Yamate J, Ogata K, Yuasa T, Kuwamura M, Takenaka S, Kumagai D, Itoh K, Lamarre J.
Adipogenic, osteogenic and myofibrogenic differentiations of a rat malignant fibrous histiocytoma (MFH)-derived cell line, and a relationship of MFH cells with embryonal mesenchymal, perivascular and bone marrow stem cells.
Eur J Cancer 43(18): 2747-2756, 2007 doi: 10.1016/j.ejca.2007.10.021.

Yamate J, Yamamot E, Nabe M, Kuwamura M, Fujita D, Sasai H
Spontaneous adenocarcinoma immunoreactive to cyclooxygenase-2 and transforming growth factor-b1 in the buccal salivary gland of a Richardson’s ground squirrel (Spermophilus richardsonii)
Exp Anim 56 (5), 379-384, 2007

Hasegawa M, Takenaka S, Kuwamura M, Yamate J, Tsuyama S.
Urinary metabolic fingerprinting for amiodarone-induced phospholipidosis in rats using FT-ICR MS.
Exp Toxicol Pathol 59(2):115-20,2007 doi: 10.1016/j.etp.2007.04.001.

Sugiura T, Matsuyama S, Akiyosi H, Takenaka S, Yamate J, Kuwamura M, Aoki M, Shimada T, Ohashi F, Kubo K.
Expression patterns of the BRCA1 splicing variants in canine normal tissues and mammary gland tumors.
J Vet Med Sci 69(6):587-92,2007 doi: 10.1292/jvms.69.587.

Kuwamura M, Sawamoto O, Yamate J, Aoki M, Ohnishi Y, Kotani T.
Pulmonary vascular proliferation and lungworm (Stenurus ovatus) in a bottlenose dolphin (Tursiops turncatus).
J Vet Med Sci 69(5):531-3,2007 doi: 10.1292/jvms.69.531.

Yamate J, Sakamori M, Kuwamura M, Kotani T.
Neoplastic and non-neoplastic cell lines from a malignant peripheral nerve sheath tumour of the cervix of a rat.
J Comp Pathol 137(1):9-21,2007 doi: 10.1016/j.jcpa.2007.03.004.

Yamate J, Tomita A, Kuwamura M, Mitsunaga F, Nakamura S.
Spontaneous peritoneal malignant mesothelioma in a geriatric japanese macaque (Macaca fuscata).
Exp Anim 56(2):155-9,2007 doi: 10.1538/expanim.56.155.

Yamate J, Fumimoto S, Kuwamura M, Kotani T, LaMarre J
Characterization of a rat subcutaneous malignant fibrous histiocytoma and its tumor lines, with reference to histiocytic features.
Vet Pathol 44: 151-160, 2007 doi: 10.1354/vp.44-2-151.

Yamate J, Kotera T, Kuwamura M, Kotani T
Potential osteogenic differentiation of cisplatin-resistant rat malignant fibrous histiocytoma-derived cell lines.
Exp Toxicol Pathol 58: 299-309, 2007 doi: 10.1016/j.etp.2006.11.008.

(2006)

Chang LS, Jacob A, Lorenz M, Rock J, Akhmametyeva EM, Mihai G, Schmalbrock P, Chaudhury AR, Lopez R, Yamate J, John MR, Wickert H, Neff BA, Dodson E, Welling DB.
Growth of benign and malignant schwannoma xenografts in severe combined immunodeficiency mice.
Laryngoscope 116(11):2018-26,2006 doi: 10.1097/01.mlg.0000240185.14224.7d.

Tanno T, Tanaka Y, Sugiura T, Akiyoshi H, Takenaka S, Kuwamura M, Yamate J, Ohashi F, Kubo K, Tsuyama S
Expression patterns of the slit subfamily mRNA in canine malignant mammary tumors.
J Vet Med Sci 68: 1173-1177, 2006 doi: 10.1292/jvms.68.1173.

Kuwamura M, Ide M, Yamate J, Shiraishi Y, Kotani T
Systemic candidiasis in a dog, developing spondylitis.
J Vet Med Sci 68: 1117-1119, 2006 doi: 10.1292/jvms.68.1117.

Yamate J, Aota M, Kuwamura M, Kotani T, Shimada T
Synovial sarcoma of the tendon and tendon sheath in a dog.
J Vet Med Sci 68: 983-986, 2006 doi: 10.1292/jvms.68.983.

Yamate J, Izawa T, Ogata K, Kobayashi O, Okajima R, Kuwamura M, Kotani T, Aoki M
Olfactory neuroblastoma in a horse.
J Vet Med Sci 68: 495-498, 2006 doi: 10.1292/jvms.68.495.

Ihara H, Atsuta M, Kuwamura M, Nihonmatsu I, Okada T, Mukamoto M, Kozaki S
Expression of neuronal nitric oxide synthase variant, nNOS-mu, in rat brain.
Nitric Oxide 15: 13-9, 2006 doi: 10.1016/j.niox.2005.11.011.

Gohma H, Kuramoto T, Kuwamura M, Okajima R, Tanimoto N, Yamasaki KI, Nakanishi S, Kitada K, Makiyama T, Asao M, Kita T, Sasa M, Serikawa T
WTC deafness Kyoto (dfk): a rat model for extensive investigation of Kcnq1 functions.
Physiol Genomics 24: 198-206, 2006 doi: 10.1152/physiolgenomics.00221.2005.

(2005)

Uehara T, Watanabe H, Itoh F, Inoue S, Koshida H, Nakamura M, Yamate J, Maruyama T.
Nephrotoxicity of a novel antineoplastic platinum complex, nedaplatin: a comparative study with cisplatin in rats.
Arch Toxicol 9(8):451-60, 2005 doi: 10.1007/s00204-005-0648-6.

Sato S, Hori Y, Yamate J, Saito T, Kurasaki M, Hatai A.
Protective effect of dietary azuki bean (Vigna angularis) seed coats against renal interstitial fibrosis of rats induced by cisplatin.
Nutrition 21(4):504-11, 2005 doi: 10.1016/j.nut.2004.07.019.

Sato S, Yamate J, Hori Y, Hatai A, Nozawa M, Sagai M.
Protective effect of polyphenol-containing azuki bean (Vigna angularis) seed coats on the renal cortex in streptozotocin-induced diabetic rats.
J Nutr Biochem 16(9):547-53, 2005 doi: 10.1016/j.jnutbio.2005.02.003.

Tanno T, Fujiwara A, Takenaka S, Kuwamura M, Tsuyama S
Expression of a chemorepellent factor Slit2 in peripheral nerve regeneration.
Biosci Biotechnol Biochem 69: 2431-2434, 2005 doi: 10.1271/bbb.69.2431.

Yamate J, Kuribayashi M, Kuwamura M, Kotani T, Ogihara K
Differential immunoexpressions of cytoskeletons in renal epithelial and interstitial cells in rat and canine fibrotic kidneys, and in kidney-related cell lines under fibrogenic stimuli.
Exp Toxicol Pathol 57: 135-147, 2005 doi: 10.1016/j.etp.2005.07.001.

Nakanishi M, Kuwamura M, Yamate J, Fujita D, Sasai H
Gastric adenocarcinoma with ossification in a ferret (Mustela putorius furo)
J Vet Med Sci 67: 939-941, 2005 doi: 10.1292/jvms.67.939.

Ide M, Kuwamura M, Kotani T, Sawamoto O, Yamate J
Effects of gadolinium chloride (GdCl3) on the appearance of macrophage populations and fibrogenesis in thioacetamide-induced rat hepatic lesions.
J Comp Pathol 133: 92-102, 2005 doi: 10.1016/j.jcpa.2005.01.011.

Tamada H, Kawate N, Inaba T, Kuwamura M, Maeda M, Kajikawa T, Sawada T
Adenomyosis with severe inflammation in the uterine cervix in a dog.
Can Vet J 46: 333-334, 2005

Yamate J, Machida Y, Ide M, Kuwamura M, Kotani T, Sawamoto O, LaMarre J
Cisplatin-induced renal interstitial fibrosis in neonatal rats, developing as solitary nephron unit lesions.
Toxicol Pathol 33: 207-217, 2005 doi: 10.1080/01926230490523978.

Kuwamura M, Muraguchi T, Matsui T, Ueno M, Takenaka S, Yamate J, Kotani T, Kuramoto T, Guenet JL, Kitada K, Serikawa T
Mutation at the Lmx1a locus probokes aberrant brain development in the rat.
Dev Brain Res 155: 99-106, 2005 doi: 10.1016/j.devbrainres.2004.12.009.

(2004)

Ide M, Kuwamura M, Kotani T, Yamate J
Immunophenotypical changes of myofibroblasts appearing in thioacetamide-induced hepatic fibrosis in rats.
J Toxicol Pathol 17: 231-238, 2004

Yamate J, Machida Y, Ide M, Kuwamura M, Sawamoto O, LaMarre J.
Effects of lipopolysaccharide on the appearance of macrophage populations and fibrogenesis in cisplatin-induced rat renal injury.
Exp Toxicol Pathol. 56: 13-24, 2004 doi: 10.1016/j.etp.2004.04.008.

Kawashima M, Kuwamura M, Takeya M, Yamate J.
Morphologic characteristics of pulmonary macrophages in cetaceans: particular reference to pulmonary intravascular macrophages as a newly identified type.
Vet Pathol. 4: 682-686, 2004 doi: 10.1354/vp.41-6-682.

Kuwamura M, Kanehara T, Tokuda S, Kumagai D, Yamate J, Kotani T, Nakane Y, Kuramoto T, Serikawa T.
Immunohistochemical and morphometrical studies on myelin breakdown in the demyelination (dmy) mutant rat.
Brain Res. 1022: 110-116, 2004 doi: 10.1016/j.brainres.2004.07.007.

Kuwamura M, Kinoshita A, Okumoto M, Yamate J, Mori N.
Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse chromosome 12.
Dev Brain Res. 152: 69-72, 2004 doi: 10.1016/j.devbrainres.2004.05.006.

Kawashima M, Nakanishi M, Kuwamura M, Takeya M, Yamate J.
Distributive and phagocytic characteristics of hepatic macrophages in five cetaceans belonging to Delphinidae and Ziphiidae.
J Vet Med Sci. 66: 671-680, 2004 doi: 10.1292/jvms.66.671.

Nakanishi M, Sawamoto O, Kawashima M, Kuwamura M, Yamate J.
Morphological changes in the parathyroid gland of rats with humoral hypercalcaemia of malignancy.
J Comp Pathol. 131: 92-97, 2004 doi: 10.1016/j.jcpa.2004.01.002.

Yamate J, Yokoyama Y, Kumagi D, Tsukamoto Y, Kuwamura M, Kotani T, Sakuma S.
Tumour lines from a spontaneous rat endometrial stromal sarcoma, showing dendritic cell-like and myofibroblastic cell-like phenotypes.
J Comp Pathol. 131: 38-51, 2004 doi: 10.1016/j.jcpa.2004.01.003.

Aoki M, Kim T, Shimada T, Kuwamura M, Yamate J, Ohashi F.
A primary hepatic plasma cell tumor in a dog.
J Vet Med Sci. 66: 445-447, 2004 doi: 10.1292/jvms.66.445.

Kuwamura M, Kotera T, Yamate J, Kotani T, Aoki M, Hori A.
Cerebral ganglioneuroblastoma in a golden retriever dog.
Vet Pathol. 41: 282-284, 2004 doi: 10.1354/vp.41-3-282.

Kuramoto T, Kuwamura M, Serikawa T.
Rat neurological mutations cerebellar vermis defect and hobble are caused by mutations in the netrin-1 receptor gene Unc5h3.
Brain Res Mol Brain Res. 122: 103-108, 2004 doi: 10.1016/j.molbrainres.2003.12.003.

Kuwamura M, Ando Y, Takada A, Kanehara T, Yamate J, Kotani T, Takeshita S, Kanbori M, Kitada K, Serikawa T.
Rat mutations cvd and hob with cerebellar malformations map to chromosome 2.
Exp Anim. 53: 21-26, 2004 doi: 10.1538/expanim.53.21.

Kawashima M, Nakanishi M, Kuwamura M, Takeya M, Yamate J
Immunohistochemical detection of macrophages in the short-finned pilot whale (Globicephala macrorhynchus) and Risso’s dolphin (Grampus griseus).
J Comp Pathol 130: 32-40, 2004 doi: 10.1016/s0021-9975(03)00066-5.

(2003)

Tsunenari I, Yamate J, Iwaki M, Kuwamura M, Kotani T, Sakuma S.Angioarchitecture of tumors induced by two different cloned cell lines established from a transplantable rat malignant fibrous histiocytoma.
Microsc Microanal. 9: 532-541, 2003 doi: 10.1017/S1431927603030289.

柴崎 哲、山下美佳、進学之、木下麻子、桑村 充、山手丈至、片本 宏、野村紘一
2本の短絡血管を認めた犬の肝外門脈体循環短絡症の一治験例
日本獣医師会雑誌 56:531-534, 2003.

Sawamoto O, Yamate J, Kuwamura M, Kotani T
Age-dependent decrease of rat sperm granulomas.
J Toxicol Pathol 16: 123-127, 2003

Sawamoto O, Kurisu K, Kuwamura M, Kotani T, Yamate J.
Relationship of interstitial edema with L-cysteine-induced sperm granulomas in the pubertal rat epididymis.
Exp Toxicol Pathol. 55: 121-127, 2003 doi: 10.1078/0940-2993-00316.

Nakanishi M, Kuwamura M, Ueno M, Yasuda K, Yamate J, Shimada T.
Pulmonary adenocarcinoma with osteoblastic bone metastases in a cat.
J Small Anim Pract. 44: 464-466, 2003 doi: 10.1111/j.1748-5827.2003.tb00107.x.

Sawamoto O, Yamate J, Kuwamura M, Kotani T, Kurisu K.
Macrophage populations in L-cysteine-induced rat sperm granulomas.
J Comp Pathol. 129: 308-312, 2003 doi: 10.1016/s0021-9975(03)00043-4.

Nakanishi M, Ide M, Kawashima M, Kuwamura M, Kumagai D, Sawamoto O, Yamate J.
Establishment of a transplantable rat pulmonary carcinoma-derived cell line (IP-B12) as a new model of humoral hypercalcemia of malignancy and bone metastasis.Tumour Biol. 24: 70-6, 2003 doi: 10.1159/000071079.

Katamoto H, Kumagai D, Kouzai N, Takigami S, Kuwamura M, Yamate J, Kotani T.Space-occupying leiomyoma in the pelvic canal of a dog.
J Small Anim Pract. 44: 277-279, 2003 doi: 10.1111/j.1748-5827.2003.tb00156.x.

Yamate J, Yasui H, Benn SJ, Tsukamoto Y, Kuwamura M, Kumagai D, Sakuma S, LaMarre J.
Characterization of newly established tumor lines from a spontaneous malignant schwannoma in F344 rats: nerve growth factor production, growth inhibition by transforming growth factor-beta1, and macrophage-like phenotype expression.Acta Neuropathol (Berl). 106: 221-233, 2003 doi: 10.1007/s00401-003-0723-0.

Kuwamura M, Hattori R, Yamate J, Kotani T, Sasai K.
Neuronal ceroid-lipofuscinosis and hydrocephalus in a chihuahua.
J Small Anim Pract. 44: 227-230, 2003 doi: 10.1111/j.1748-5827.2003.tb00148.x.

Sawamoto O, Yamate J, Kuwamura M, Kotani T, Kurisu K.
Development of sperm granulomas in the epididymides of L-cysteine-treated rats.Toxicol Pathol. 31: 281-289, 2003 doi: 10.1080/01926230390204315.

Kawashima M, Ide M, Nakanishi M, Kuwamura M, Kumagai D, Yamate J.Immunophenotypical changes of neoplastic cells and tumor-associated macrophages in a rat dendritic cell sarcoma-derived transplantable tumor line (KB-D8).
Virchows Arch. 442: 141-150, 2003 doi: 10.1007/s00428-002-0716-8.

Ide M, Yamate J, Machida Y, Nakanishi M, Kuwamura M, Kotani T, Sawamoto O.Emergence of different macrophage populations in hepatic fibrosis following thioacetamide-induced acute hepatocyte injury in rats.
J Comp Pathol. 128: 41-51, 2003

Hori Y, Sato S, Yamate J, Kurasaki M, Nishihira J, Hosokawa T, Fujita H, Saito T.
Immunohistochemical study of macrophage migration inhibitory factor in rat liver fibrosis induced by thioacetamide.
Eur J Histochem. 47: 317-324, 2003

Mori N, Yamate J, Umesako S, Hong DP, Okumoto M, Nakao R.
Preferential induction of mammary tumors in p53 hemizygous BALB/c mice by fractionated irradiation of a sub-lethal dose of X-rays.
J Radiat Res (Tokyo). 44: 249-254, 2003 doi: 10.1269/jrr.44.249.

Kumagai D, Shimada T, Yamate J, Ohashi F.
Use of an incontinent end-on colostomy in a dog with annular rectal adenocarcinoma.
J Small Anim Pract. 44: 363-366, 2003 doi: 10.1111/j.1748-5827.2003.tb00169.x.

(2002)

Nakanisi M, Kuwamura M, Yamate J, Aoki M, Uchida T
Calcifying epithelial odontogenic tumor in a dog.
J Toxicol Pathol 15: 171-173, 2002

Kuwamura M, Adachi T, Yamate J, Kotani T, Ohashi F, Summers BA.
Necrotising encephalitis in the Yorkshire terrier: a case report and literature review.
J Small Anim Pract. 43: 459-463, 2002 doi: 10.1111/j.1748-5827.2002.tb00014.x.

Kuwamura M, Maeda M, Kuramoto T, Kitada K, Kanehara T, Moriyama M, Nakane Y, Yamate J, Ushijima T, Kotani T, Serikawa T.
The myelin vacuolation (mv) rat with a null mutation in the attractin gene.
Lab Invest. 82: 1279-1286, 2002 doi: 10.1097/01.lab.0000032375.70196.26.

Yamate J, Kuriyama T, Kawashima M, Nakanishi M, Ide M, Kuwamura M, Tsukamoto Y, Kotani T, Nakatsuji S.
Establishment and characterization of transplantable tumor line (KB) and cell lines (KB-P and KB-D8) from a rat thymus-derived dendritic cell sarcoma.
Virchows Arch. 440: 616-626, 2002 doi: 10.1007/s00428-001-0595-4.

Yamate J, Sato K, Ide M, Nakanishi M, Kuwamura M, Sakuma S, Nakatsuji S.Participation of different macrophage populations and myofibroblastic cells in chronically developed renal interstitial fibrosis after cisplatin-induced renal injury in rats.
Vet Pathol. 39: 322-333, 2002 doi: 10.1354/vp.39-3-322.

Nakanishi M, Yamate J, Nakatsuji S, Ide M, Sawamoto O, Kuwamura M, Kotani T, Sakuma S.
Establishment of a transplantable tumor line (IP) derived from rat pulmonary carcinoma, developing humoral hypercalcemia of malignancy in IP-bearing rats.Virchows Arch. 440: 195-204, 2002 doi: 10.1007/s004280100484.

Sato S, Yamate J, Saito T, Hosokawa T, Saito S, Kurasaki M.
Protective effect of taurine against renal interstitial fibrosis of rats induced by cisplatin.
Naunyn Schmiedebergs Arch Pharmacol. 365: 277-283, 2002 doi: 10.1007/s00210-001-0524-8.

Tsunenari I, Yamate J, Sakuma S.
Three-dimensional angioarchitecture in transplantable rat fibrosarcomas.
J Comp Pathol. 126:66-70, 2002 doi: 10.1053/jcpa.2001.0505.

Ide M, Yamate J, Machida Y, Sawamoto O, Nakanishi M, Kuwamura M, Kotani T, Sakuma S
Macrophage populations, myofibroblastic cells, and extracellular matrix accumulation in chronically-developing rat liver cirrhosis induced by repeated injection of thioacetoamide.
J Toxicol Pathol 15: 19-29, 2002

(2001)

Yamate J, Maeda M, Benn SJ, Laithwaite JE, Allan A, Ide M, Kuwamura M, Kotani T, Sakuma S, Lamarre J.
Differential effects of transforming growth factor-beta1, a fibrogenic factor, on macrophage-like cells (HS-P) and myofibroblastic cells (MT-9) in vitro.
Toxicol Pathol. 29: 483-491, 2001 doi: 10.1080/01926230152500103.

Matsuzaki J, Kuwamura M, Yamaji R, Inui H, Nakano Y.
Inflammatory responses to lipopolysaccharide are suppressed in 40% energy-restricted mice.
J Nutr. 131: 2139-2144, 2001 doi: 10.1093/jn/131.8.2139.

Yamate J, Maeda M, Benn SJ, Laithwaite JE, Allan A, Ide M, Kuwamura M, Kotani T, Sakuma S, LaMarre J.
Effects of lipopolysaccharide on a macrophage-like cell line (HS-P) from a rat histiocytic sarcoma.
J Comp Pathol. 125: 15-24, 2001 doi: 10.1053/jcpa.2001.0472.

Ide M, Yamate J, Kuwamura M, Kotani T, Sakuma S, Takeya M.Immunohistochemical analysis of macrophages and myofibroblasts appearing in hepatic and renal fibrosis of dogs.
J Comp Pathol. 124: 60-69, 2001 doi: 10.1053/jcpa.2000.0429.

Kumagai D, Yamate J, Tajima T, Kuwamura M, Kotani T, Sakuma S.
Malignant fibrous histiocytoma (MFH) cells and macrophages/histiocytes have a common antigen recognized by a monoclonal antibody risen against a rat MFH-derived cloned cell line.
J Vet Med Sci. 63: 333-335, 2001 doi: 10.1292/jvms.63.333.

Yamate J, Maeda M, Tsukamoto Y, Benn SJ, Laithwaite JE, Allan A, Kannan Y, Ide M, Kuwamura M, Kotani T, Sakuma S, LaMarre J.
Macrophage-like cell line (HS-P) from a rat histiocytic sarcoma.
J Comp Pathol. 2001 Feb-Apr;124(2-3):183-91. doi: 10.1053/jcpa.2000.0452.

Mori N, Matsumoto Y, Okumoto M, Suzuki N, Yamate J
Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis.
Oncogene 20: 3609-3619, 2001 doi: 10.1038/sj.onc.1204497.

Nakanishi M, Yamate J, Ide M, Sawamoto O, Kuwamura M, Kotani T, Nakatsuji S
Humoral hypercalcemia of malignancy in female F344 rats implanted with a transplantable rat pulmonary carcinoma line (IP).
J Vet Med Sci 63: 1135-1138, 2001 doi: 10.1292/jvms.63.1135.

(2000)

Mori N, Okumoto M, Yamate J A susceptibility locus for radiation lymphomagenesis on mouse chromosome 16. J Radiat Res 41: 367-372, 2000 doi: 10.1269/jrr.41.367.

Kuwamura M, Morikawa T, Yasui H, Yamate J, Kotani T Dandy-Walker malformation in a Fischer-344 rat. Toxicol Pathol 28: 694-696, 2000 doi: 10.1177/019262330002800509.

Kannan Y, Moriyama M, Sugano T, Yamate J, Kuwamura M, Kagaya A, Kiso Y Neurotrophic action of interleukin 3 and granulocyte-macrophage colony-stimulating factor on murine sympathetic neurons. Neuroimmunomodulation 8: 132-141, 2000 doi: 10.1159/000054273.

Naganobu K, Ogawa H, Uchida K, Yamaguchi R, Ohashi F, Kubo K, Aoki M, Kuwamura M, Ogawa Y, Matsuyama K Mast cell tumor in the nasal cavity of a dog. J Vet Med Sci 62: 1009-1011, 2000 doi: 10.1292/jvms.62.1009.

Kuwamura M, Ide M, Kuribayashi M, Yamate J, Nomura K, Kotani T Malignant melanoma with cartilaginous formation in a dog. J Toxicol Pathol 13: 269-270, 2000

Yamate J, Sato K, Machida Y, Ide M, Sato S, Nakatsuji S, Kuwamura M, Kotani T, Sakuma S Cisplatin-induced rat renal interstitial fibrosis: a possible pathogenesis based on the data. J Toxicol Pathol 13: 237-347, 2000

Aoki M, Kubo K, Kuwamura M, Kotani T, Matsuyama S, Shibazaki A, Shimada T, Ohashi F Successful management of canine acanthomatous epulis with the combination of surgical excision and radiotherapy. Jpn J Vet Anesth Surg 31: 37-41, 2000

Sasai H, Kato K, Sasaki S, Kotani T, Fukata T Echocardiographic diagnosis of dirofilariasis in a ferret. J Small Anim Pract 41: 172-174, 2000 doi: 10.1111/j.1748-5827.2000.tb03189.x.

Tsunenari I, Yamate J, Sharmal KD, Kawauchi M, Sakuma S Expressions of vascular endothelial growth factor and basis fibroblast growth factor in tumors induced by two different cloned cell lines established from transplantable rat malignant fibrous histiocytoma. J Vet Med Sci 62: 699-705, 2000

Kuwamura M, Kanehara T, Yamate J, Shimada T, Kotani T Amyoid producing odontogenic tumor in a Shih-Tzu dog. J Vet Med Sci 62: 655-657, 2000 doi: 10.1292/jvms.62.655.

Yamate J, Yoshida H, Tsukamoto Y, Ide M, Kuwamura M, Ohashi F, Miyamoto T, Kotani T, Sakuma S, Takeya M Distribution of cells immunopositive for AM-3K, a novel monocolonal antibody recognizing human macrophages, in normal and diseased tissues of dogs, cats, horse, cattle, pigs, and rabbits. Vet Pathol 37: 168-176, 2000 doi: 10.1354/vp.37-2-168.

Mizuno T, Kannan Y, Tokunaga M, Moriyama M, Kiso Y, Kusakabe K., Yamate J, Kiyomiya K., Sugano T. Role of hypothermia induced by tumor necrosis factor on apoptosis and function of inflammatory neutrophils in mice. Am J Physiol 278: R157-165, 2000 doi: 10.1152/ajpregu.2000.278.1.R157.

Kumagai D, Yamate J, Tajima T, Tsukamoto Y, Yasui H, Kuwamura M, KotaniT, Sakuma S. Distribution of cells labelled by a monoclonal antibody (A3) against a cloned cell line dereived from a rat malignant fibrous histiocytoma. J Comp Pathol 123: 77-87, 2000 doi: 10.1053/jcpa.2000.0389.

Kotani T, Shiraishi Y, Tsukamoto Y, Kuwamura M, Yamate J, Sakuma S, Gohda M Epithelial cell kinetics in the inflammatory process of chicken trachea infected with infectious bronchitis virus. J Vet Med Sci 62: 129-134, 2000 doi: 10.1292/jvms.62.129.

Kotani T, Wada S, Tsukamoto Y, Kuwamura M, Yamate J, Sakuma S Kinetics of lymphocytic subsets in chicken tracheal lesions infected with infectious bronchitis virus. J Vet Med Sci 62: 397-401, 2000 doi: 10.1292/jvms.62.397.

Kuwamura M, Shirota A, Takada A, Yamate J, Kotani T, Sakuma S
Spontaneous and ethyl-nitrosourea-induced medullomyoblastomas in cerebellar vermis defect (CVD) mutant rats.
Acta Neuropathol 99: 285-288, 2000 doi: 10.1007/pl00007439.

Kuwamura M, Morikawa T, Yamate J, Kato K, Kotani T, Sakuma S Glial pathology in development of cerebellar dysplasia in the hereditary cerebellar vermis defect (CVD) rat. Acta Neuropathol 99: 305-309, 2000 doi: 10.1007/pl00007442.